This book was first published in 1994. Vitamins are essential micronutrients available to animal organisms through the diet. This book takes a fresh approach to vitamin-binding proteins, with emphasis on the nature of the binding of the vitamin ligand to a protein and its sequela. The role of vitamin-binding proteins as initiators of the metabolic response is evaluated. Experts in the field from around the world present an account of their work on the interaction of vitamins with specific intracellular systems through the appropriate binding proteins and how this interaction results in the biological action of vitamins. The book will be of interest to research workers and postgraduate students in the field of biochemistry and nutrition.