When a grafted part fails to take, it is usually because of acute or chronic rejection, either for strictly immunological reasons or because of failure to properly follow the immunosuppressive therapy. There are other reasons for loss of a transplant however, notably when the disease that led to a kidney transplant returns after the operation, something that happens in 5 to 15% of cases. This book aims to: Review the current state of knowledge and methods of care; Suggest therapeutic consensus, especially in cases of nephrotic syndrome, by using specific post-transplant treatment or preventive measures; Connect up the various practices concerning choice of donors; Spell out more clearly the approach to take when a first transplant fails and another is envisaged; Sponsored by the Mérieux Foundation and the work of leading international experts in the field, the book provides indispensable top-quality information.