Mass spectrometry has proven its applicability to the measurement of almost any molecule. However, different substances require special knowledge in the respective field and scientists tend to focus on their particular task in collaborations and meetings. Nevertheless, disciplines have become more and more interdisciplinary and scientists now have to acquire knowledge in many scientific fields other than our own, especially, mass spectrometrists who often find themselves learning about the history of their sample, be it from a zoologist, clinician, microbiologist, or biochemist. This was evident with the rise of proteomics, which reaches across species and research projects, uniting scientists through the methodology. This book covers research in the fields of biomacromolecules such as proteins, DNA, and other biopolymers studied with mass spectrometry.