Computerized medical imaging and image analysis have been the central focus in diagnostic radiology. They provide revolutionarizing tools for visualization of physiology as well as the understanding and quantitative measurement of physiological parameters. This book provides a unique depth of knowledge from the principles to recent advanced methods in medical imaging instrumentation and techniques as well as multidimensional image analysis and classification methods for research, education and applications in computer-aided diagnostic radiology. Internationally renowned researchers and experts in their respective areas provide detailed description of the basic foundation as well as the most recent developments in medical imaging. This book helps readers to understand theoretical and advanced concepts for important research and clinical applications.