Systems biology is the study of organisms as interacting networks of genes, proteins and reactions.Practical Systems Biologyprovides a detailed overview of the different approaches used in this relatively new discipline, integrating bioinformatics, genomics, proteomics and metabolomics. Various areas of research are also discussed, including the use of computational models of biological processes, and post-genomic research.This SEB symposium volume, based upon topics presented in the SEB conference of July 2006, is written by respected researchers and gives an excellent account of various issues of systems biology that is suitable for postgraduate and postdoctoral researchers who are interested in this expanding area of science.