As with her previous work What the Angels Need to Tell Us Now, More Messages from the Angels is divided into two parts. In the first section, Irene Johanson gives valuable advice about the inner preparations necessary to receive angel messages in the proper way. She explains how to distinguish between the different kinds of spirits, and how to deal with information received from metaphysical entities--in particular knowing whether such information is genuine or not. She also gives advice about transforming our life of soul and the forces of thinking, feeling and will.

In the second part, Johanson presents more messages and information received from angels through her friend Agnes, an individual who represents a new kind of clairvoyance. Unlike mediumism or channeling, Agnes's method does not entail a dimming of consciousness, but has the character of clarity and wakefulness. The messages received contain critical advice, guidance and insight from the angels to humanity. This time they speak on many contemporary issues, including organ transplants, genetic modification, cloning, "mad cow disease," nuclear energy, evil, catastrophes and disasters (including 9 / 11), abortion, population growth, sudden death, cyanide, AIDS, sexuality, difficult children, fear, psychological warfare, ecumenism, democracy, and human and angelic cooperation.