Cover -- Title -- Copyright -- THE AUTHORS -- Dedication -- FOREWORD -- ACKNOWLEDGMENTS -- TABLE OF CONTENTS -- Part 1: Methyl Chloroform -- Chapter 1: Introduction to Methyl Chloroform -- Chapter 2: Review of the Literature on Methyl Chloroform -- A: Chemical and Physical Properties -- B: Industrial Uses -- C: Aerosol Products -- 1: Hair sprays and cosmetics -- 2: Medicated vapors -- 3: Consumer aerosol products -- D: Human Investigation -- 1: Fatalities in confined spaces -- 2: Nonindustrial fatalities -- 3: Experimental inhalation -- 4: Inspired and expired concentrations -- 5: Urinary excretion -- E: Absorption, Metabolism, and Disposition in Animals -- F: Toxicologic Investigation in Animals -- 1: Oral administration -- 2: Intraperitoneal injection -- 3: Inhalation toxicity: single exposure -- 4: Inhalation toxicity: repeated exposures -- G: Pharmacodynamic Effects -- 1: General anesthetic -- 2: Cardiotoxicity -- 3: Pneumotoxicity -- 4: Hepatotoxicity -- 5: Nephrotoxicity -- 6: Dermatotoxicity -- 7: Embryo and fetotoxicity -- H: Clinical Toxicology -- I: Threshold Limit Values (TLV) for Methyl Chloroform -- J: Conversion Table for Concentrations of Methyl Chloroform -- Chapter 3: Acute lnhalational, Oral, and Intraperitoneal of Methyl Chloroform Toxicity in Mice -- A: Methods -- B: Results -- C: Discussion -- 1: LD50 -- 2: Electrocardiographic changes -- 3: Correlation between LD50 and electrocardiographic changes -- D: Summary -- Chapter 4: Acute Inhalational Toxicity of Methyl Chloroform in Dogs -- A: Methods -- B: Calculations and Abbreviations of Hemodynamic Measurements -- C: Results -- 1: Administration of methyl chloroform -- 2: Administration of a mixture of subeffective concentrations of methyl chloroform and trichlorofluoromethane (FC 11) -- D: Discussion -- E: Summary -- Chapter 5: Summary of Toxicity of Methyl Chloroform