This book examines the institutional roots of the persistent differences in economic performance of firms, industries and countries in Africa. It draws attention to the role of institutions in supporting technical change and shows how technological progress is central to competitiveness in a global context. The role of initial conditions such as levels of literacy and natural endowment, the structure of industry and resource endowment are also emphasized. With its focus on how institutions shape systems of innovation this book makes a unique contribution to the debate about African development.