This book begins with the assumption that a deep understanding of the origins of psychopathology, human dysfunction, and their course is fundamental to the quest for the good society, and perhaps, even to our survival as a species. The studies presented compare prevalences and risk factors across time and place, and make use of concepts and methods from history, geography, sociology, anthropology, economics, psychology, social and medical services research, social policy, psychiatry, and epidemiology. Collectively, they illustrate the methods and methodological difficulties involved in the effort to achieve a deep understanding and provide important insights into the disorders and dysfunctions that are investigated.