This volume constitutes selected papers presented at the First International Conference on Frontiers in Software Engineering, ICFSE 2021, hekd in Innopolis, Russia, in June 2021. The 13 presented full papers were thoroughly reviewed and selected from 37 submissions. The papers present discussion on such topics as software engineering tools and environments; empirical software engineering; model-driven and domain-specific engineering, human factors and social aspects of software engineering, cooperative, distributed, and global software engineering, component-based software engineering, software metrics, and software engineering for green and sustainable technologies.