Enola Holmes is the much younger sister of her more famous brothers, Sherlock and Mycroft. But she has all the wits, skills, and sleuthing inclinations of them both. At fifteen, she's an independent young woman and living on her own in London. When a young professional woman, Miss Letitia Glover, shows up on Sherlock's doorstep, desperate to learn more about the fate of her twin sister, it is Enola who steps up. It seems her sister, the former Felicity Glover, married the Earl of Dunhench and per a curt note from the Earl, has died. But Letitia Glover is convinced this isn't the truth, that she'd know, she'd feel, if her twin had died. The Earl's note is suspiciously vague and the death certificate is even more dubious, signed it seems by a John H. Watson, M.D. (who denies any knowledge of such). The only way forward is for Enola to go undercover, or so Enola decides at the vehement objection of her brother. And she soon finds out that this is not the first of the Earl's wives to die suddenly and vaguely.