"Doctor Therne" is a novel by H. Rider Haggard. The story revolves around the life of James Therne, a physician in the city of Dunchester who becomes embroiled in controversy after advocating against compulsory smallpox vaccinations. A smallpox epidemic then breaks out in the city, killing thousands, and Therne is haunted by guilt for his role in the disaster. The novel explores themes of morality, guilt, and redemption, as well as the dangers of anti-vaccination movements. It also delves into the complexities of relationships, as Therne struggles to reconcile his love for his daughter with his guilt over her death. Overall, "Doctor Therne" is a thought-provoking novel that raises important questions about the responsibilities of those in positions of authority and the consequences of their actions.