This book investigates key aspects of the development of engaged and entrepreneurial universities. Reflecting the complex and dynamic nature of changes in higher education institutions (HEIs), multi-level perspectives in the field are taken into account, namely the ecosystem, relationship, organisational and individual perspective. The book highlights the entrepreneurial and the social orientation of HEIs by focusing on both primary economically focused (entrepreneurial) universities and primary socially focused (engaged) universities. It challenges the understanding of the role universities and its individual stakeholders play today. The book explores a multitude of facets and perspectives on the topic and addresses both what we already know and what knowledge still needs to be acquired.