Chapter 1 Microbial Genome Mining for Natural Product Drug Discovery -- chapter 2 Chemical Biology of Marine Cyanobacteria -- chapter 3 The Role of Combinatorial Biosynthesis in Natural Products Discovery -- chapter 4 Generation of New-to-Nature Natural Products through Synthesis and Biosynthesis: Blending Synthetic Biology with Synthetic Chemistry -- chapter 5 Terrestrial Microbial Natural Products Discovery Guided by Symbiotic Interactions and Revealed by Advanced Analytical Methods -- chapter 6 Natural Products from Endophytic Microbes: Historical Perspectives, Prospects, and Guidance -- chapter 7 Novel Insights in Plant-Endophyte Interactions -- chapter 8 Microbial Coculture and OSMAC Approach as Strategies to Induce Cryptic Fungal Biogenetic Gene Clusters -- chapter 9 Natural Products of the Rhizosphere and Its Microorganisms: Bioactivities and Implications of Occurrence -- chapter 10 Novel Metabolites from Extremophilic Microbes Isolated from Toxic Waste Sites -- chapter 11 Deep-Sea Hydrothermal Vent Organisms as Sources of Natural Products -- chapter 12 Cone Snail Venom Peptides and Future Biomedical Applications of Natural Products -- chapter 13 Naturally Occurring Disulfide-Rich Cyclic Peptides from Plants and Animals: Synthesis and Biosynthesis -- chapter 14 Synthesis and Target Identification of Natural Product-Inspired Compound Collections -- chapter 15 On the Chemistry and Biology of the Marine Macrolides Zampanolide and Dactylolide.