In this book on practical antibiotherapy in swine medicine, the author has tried to present, in a visual and practical way and with an updated view, the most important aspects a veterinary clinician should take into account to design appropriate antimicrobial treatments in swine herds. Thus, in this work, current pharmacological knowledge is reviewed with the help of real clinical cases solved by the author. Finally, it includes a comprehensive review of what a prudent use of these essential tools to ensure our animals? health means. This book has been prepared with all the veterinary professionals who dedicate themselves to clinical practice in mind, with the idea that it may be a useful reference tool. In addition, the author has structured the content in a way that will allow clinicians to reflect on the reasons for administering a particular drug treatment and to carry out a self-assessment of their work.