Using an innovative approach to evidence for the medieval hospital and medical practice, this collection of essays presents new research by leading international scholars in creating a holistic look at the hospital as an environment within a social and intellectual context. The research presented creates insights into practice, medicines, administration, foundation, regulation, patronage, theory, and spirituality. Looking at differing models of hospital administration between 13th century France and Spain, social context is explored. Seen from the perspective of the history of Knights of the Order of Saint Lazarus, and Order of the Temple, hospital and practice have a different emphasis. Extant medieval hospitals at Tonnerre and Winchester become the basis for exploring form and function in relation to health theory (spiritual and non-spiritual) as well as the influence of patronage and social context. In the case of the Ospedale Maggiore in Milan, this line of argument is taken further to demonstrate aspects of the building based on a concept of epidemiology. Evidence for the practice of medicine presented in these essays comes from a variety of sources and approaches such as remedy books, medical texts, recorded practice, and by making parallels with folk medicine. Archaeological evidence indicates both religious and non religious medical intervention while skeletal remains reveal both pathology and evidence of treatment.