Managing in Four Worlds is the first business book to focus simultaneously on physical and human nature, as embodied in culture, as the basis for sustainable business development internationally. The authors combine key concepts from the new physics, developmental psychology and ecology to develop a theory and practice of business that can be applied anywhere in the world.

The book draws upon the four main major cultures from around the globe- pragmatism, rationalism, holism and humanism - and combines threads from each to create a new, commercially effective and psychologically fulfilling approach to enterprise and work. In doing so, the approach that Lessem and Palsule take straddles the culture and approaches the culture and approaches of the North, South, East, and West. They have created an entirely original overarching theory of business that applies simultaneously to organizational learning, business innovation, and managing across cultures.