"In the multi-disciplinary area of drug discovery/design, a strong background in chemistry was always deemed an asset. However, some paradigm shifts have taken place in basic and essential biochemistry. The distinction between enzymes and non-catalytic proteins is blurring; disorder is equally important as structure in dictating protein function. Drug promiscuity and protein promiscuity have been identified as the basis of drug repurposing. This book aims at being a stand-alone volume to capture these paradigm shifts. Apart from discussing current applications, the book will empower readers to explore possibilities where drug repurposing may offer a way out. This is vital for affordable drugs for orphan diseases; the pharma industry is not enthusiastic in investing efforts due to the small market size"-- Provided by publisher.